CONTENTS OF SH-GROUPS IN THE PERIPHERAL BLOOD PLASMA OF THE SHEEP IN CHRONIC ARRIVAL OF LEAD WITH RATION

DOI: 10.36871 / vet.san.hyg.ecol.201801018
UDC: 577.112: 636.3; 546.815

Authors

E.B. MIRZOEV, DR. BIOL SCIENCES, LEADING SCIENTIFIC EMPLOYEE
V.O. KOBYALKO, CAND. BIOL. SCIENCE HEAD OF THE LABORATORY
O. A. GUBINA, SCIENTIFIC EMPLOYEE
N.A. FROLOVA, CAND. BIOL. SCIENCE, SCIENTIFIC FGBNU "ALL-RUSSIAN RESEARCH INSTITUTE OF RADIOLOGY AND AGROECOLOGY"

Abstract

We studied the content of SH-groups in the plasma of the peripheral blood of sheep, which for 90 days received with the diet lead nitrate in concentrations of 5 (1 MDU), 25 (5 MDU) and 150 mg / kg of feed (30 MDU). It is shown that the chronic intake of lead in the body of sheep leads to a decrease in the content of SH-groups in the plasma of peripheral blood. The most pronounced nature of the changes was noted at a concentration of lead in the diet of 25 mg / kg (5 MDU) and 150 mg / kg of feed (30 MDU). It is assumed that with an increase in the concentration of lead in the organs and tissues of mammals, the processes of formation of reactive oxygen species are initiated, which lead to the oxidative modification of proteins and lipids.

Keywords

lead, sheep, peripheral blood plasma, SH-groups.