DOI: 10.36871 / VET.SAN.HYG.ECOL.202001014
UDC 619: 615: 614.9

Authors

ZAKHAROVA L.L., ZHOROV G.A., OBRYVIN V.N., BRICHKO N.A.
Institute of Veterinary Sanitation, Hygiene and Ecology - BRANCH of FSBI Federal Research Center of the Russian Academy of Science and Technology

Abstract

Livestock farming under modern conditions of anthropogenic pressure on the biosphere is a complex of problems, including the tasks of developing and applying effective tools and methods to prevent the entry and accumulation of xenobiotics in animals, as well as a number of closely related issues (deficiency of micro and macro elements in soils, feeds and the body, immune deficiency, the effects of oxidative stress and other factors). Therefore, in zones of ecological distress for the effective implementation of general detoxification and increasing the immune status of animals, animal husbandry technology should include the combined use of antioxidants, immunomodulators, adaptogens, vitamins, micro and macrocells, and other biologically active substances in the form of sorption-detoxifying complexes along with sorbing substances. Sorption-detoxifying agents, especially when used in conditions of combined chronic intake of toxicants, in addition to high detoxification properties for xenobiotics with different mechanisms of toxic action, must meet a number of requirements, among which the most important are their safety for humans and animals, the lack of interaction of components, negatively affecting the effectiveness, and the absence of a negative effect on the products obtained in conditions of prolonged practical use.

Keywords

toxic elements, cadmium, lead, sorption-detoxifying complexes, white rats, weight ratios, hematological parameters.