DOI: 10.36871 / vet.san.hyg.ecol.202003014
UDC 619: 615
Authors
Dorozhkin V.I., Pavlenko G.I., Brichko N.A., Pavlova N.S., Drozdov D.A.
All-Russian Research Institute of Veterinary Sanitation, Hygiene and
Ecology – Branch of Federal State Budget Scientific Institution
«Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko
All-Russian Research Institute of Experimental
Veterinary Medicine, Russian Academy of Sciences»
Moscow, Russian Federation
Abstract
The feed additive L-cysteine in a therapeutic dose was used for 2 months against the background of poisoning of white rats with a combination of lead and cadmium at a level of 10 MPC (50 and 5 mg / kg, respectively). The maximum accumulation of heavy metals was found in the kidneys (Pb up to 8,15 mg / kg, Cd 2,51 mg / kg) and liver (Pb up to 7,44 mg / kg, Cd 1,80 mg / kg) of rats. With the introduction of L-cysteine into the feed, the content of lead decreased by 2 times and cadmium by 2 ... 4 times in all investigated organs.
Thus, L-cysteine has shown a fairly complete protective effect in heavy metal
poisoning and can be recommended as a means that can reduce heavy metal (HM)
intoxication.
Keywords
toxicity, protector, L-cysteine, feed additive, cadmium, lead.
