ASSESSMENT OF PURITY OF PROPOLIS ON OKSITETRATSIKLIN'S PRESENCE BY HPLC METHOD

DOI: 10.36871 / vet.san.hyg.ecol.202101007
UDC 619: 614.31: 638.1

Authors

Smirnov A.M.
Klochko R.Т.
Lugansky S.N.
Galimova V.P.
Sokhlikov A.B.
Ignatieva G.I.
Blinov A.V.
All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal State Budget Scientific Institution «Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences» Moscow, Russian Federation

Abstract

The technique of detection of the residues of oxytetracycline in propolis by means of chromatography HPLC is fulfilled. Operating modes of technique are fulfilled, the experimental data testimonial of reliability of use of this method for broad practical application in system of working or arbitration control of safety of bee propolis are obtained. Sensitivity of technique on oxytetracycline makes 8-12 mkg/kg. The mean of the determination is 90%, the standard deviation is 4%.

Keywords

propolis, antibiotics, oxytetracycline, high performance liquid chromatography.