THE RESULTS OF STUDYING THE EFFICIENCY OF DIATOMITE AT INTOXICATION OF ANIMALS WITH CADMIUM AND LEAD

DOI: 10.36871 / vet.san.hyg.ecol.202102018
UDC 619: 615

Authors

Dorozhkin V.I.
Pavlenko G.I.
Pavlova N.S.
Drozdov D.A.
Brichko N.A.
All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal State Budget Scientific Institution «Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences» Moscow, Russian Federation

Abstract

The combination of cadmium and lead in doses at the level of 10 MPC for feed caused in white rats a decrease in body weight and immunoglobulin content in blood serum, an increase in the summation threshold indicator, a decrease of the amount of protein in urine and SH-groups in blood serum, a significant increase in mass coefficients of the liver and kidneys. The use of diatomite as a means to reduce heavy metal intoxication slightly increased body weight. The use of means did not lead to normalization of the summation threshold indicator, did not significantly affect the content of SH-groups. In the group of animals treated with diatomite, the mass coefficients of the liver remained significantly higher than the control values. The obtained results indicate that diatomite did not show protective properties as a feed additive to reduce lead and cadmium intoxication.

Keywords

diatomite, toxicity, protector, feed additive, cadmium, lead.