UDC 636.5.087.69
doi: 10.36871/vet.san.hyg.ecol.202104016
Authors
Marina P. Marinicheva
Vladimir V. Strogov
Saratov State Agrarian University named after N.I .Vavilov, Saratov, Russian Federation
Vasiliy I. Dorozhkin
All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology –
Branch of Federal Research Center All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and
Ya.R. Kovalenko of the Russian Academy of Sciences»,
Moscow, Russian Federation
Abstract
The article presents data on the toxicological properties of the disinfectant, which includes alkyldimethylammonium propyl ketone chloride, glutaraldehyde, glyoxal. Based on the results of a series of experiments, the main parameters of the toxicity of the disinfectant were determined. For male mice, the acute toxicity LD50 was 325±14,5 mg / kg, for male rats – 350±50 mg/kg, according to the classification of GOST 12.1.007-76, the agent belongs to the 3rd hazard class. The LD50 with repeated administration of the drug was 217±13,5 mg/kg of animal weight, the cumulation coefficient was 0,67, which indicates the ability of the drug with repeated intragastric administration to accumulate in the body of animals.
Keywords
quaternary-ammonium compounds, glutaraldehyde, disinfectant, toxicity
