UDC 636.22 / 28.082.12
DOI: 10.26155/vet.zoo.bio.202001007

Authors

N. S. Marzanov
Doctor of Biological Sciences, Professor, Chief Researcher, Federal Scientific Center for Animal Husbandry - VIZH named after L.K. Ernst "(FSBI Federal Research Center VIZH named after L.K. Ernst)
D. A. Devrishov
Doctor of Biological Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Head of the Department of Immunology and Biotechnology, Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K. I. Skryabin,
D. A. Abylkasymov
Doctor of Agricultural Sciences, Professor, Tver State Agricultural Academy
S. N. Marzanova
Candidate of Biological Sciences, Associate Professor of the Department of Immunology and Biotechnology, Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K. I. Skryabin,
N.V. Konovalova
Senior Researcher, All-Russian Research Institute of Agricultural Biotechnology (FSBI VNIISB),
I. S. Libet
graduate student, Tver State Agricultural Academy

Abstract

For the first time, four dairy cattle breeds were analyzed for the beta casein locus. The frequency of occurrence of genotypes and alleles at the locus has been established. In the last twenty years, works have appeared related to the polymorphism of the beta-casein locus and the negative effect of some beta-casein proteins on the human body. It turned out that the β-CNA1 variant of cattle milk protein and its beta-casomorphine derivative 7, when consumed, cause serious disturbances in the human body. Based on this, we have begun work on the diagnosis of the normal β-CNA2 allele and its derivative, the abnormal β-CNA1 allele at the beta-casein locus in dairy cattle. A population-genetic analysis was carried out on the occurrence of genotypes and alleles in some cattle breeds.

Keywords

cattle, breeds, polymorphism, beta casein, genotype, alleles