DOI: 10.26155/vet.zoo.bio.202005003
UDC 619: 579.63

Authors

T. I. Skrynnikova
Candidate of Veterinary Sciences, Associate Professor of Microbiology, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
T. N. Gryazneva
Doctor of Biological Sciences, Professor, Head of the Department of Microbiology, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
Le Thi Ngoc An’
Post-graduate student of the Department of Microbiology, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation

Abstract

The article reflects the main results of studying the preventive and therapeutic effects of probiotics based on different strains of bacilli in an experiment on white mice-biological models of salmonellosis. It was found that cultures of B. subtilis VKPM 10172 and B. licheniformis VKPM 10135 strains as part of the probiotic Belolin, and the recombinant strain of B. subtilis B-10641 (DSM 24613) as part of the probiotic Vetom 1 in the experiment on white mice have a therapeutic and preventive effect in salmonellosis. While prophylactic efficacy of the probiotic Belolin was 10% higher than Vetom 1, and live weight of mice at the end of the experiment were 1,4 g more.

Keywords

probiotic, salmonellosis, white mice, bacilli.