DOI: 10.26155/vet.zoo.bio.202010002
UDC 619.1: 616-07

Authors

V. A. Kostylev
Associate Professor of Biology and Pathology of Small Domestic, Laboratory and Exotic Animals, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
V. I. Kurman
Post-graduate student of the Department of Biology and Pathology of Small Domestic, Laboratory and Exotic Animals, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
L. F. Sotnikova
Doctor of Veterinary Sciences, Professor, Head of the Department of Biology and Pathology of Small Domestic, Laboratory and Exotic Animals, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation

Abstract

C-reactive protein is a protein of the acute phase of inflammation that stimulates the immune response to the inflammatory process. In this regard, a blood test for the determination of C‑reactive protein in inflammatory and degenerative diseases of the musculoskeletal system is a mandatory study, it helps to detect not only the presence of the disease, but also to determine its stage and nature. The article presents hematological parameters in dogs with inflammatory and degenerative diseases of the musculoskeletal system and presents the role of rheumatoid factor and C-reactive protein in the pathogenesis of inflammatory and degenerative diseases of the musculoskeletal system in dogs. The statistical analysis of the obtained data revealed an increase in the total number of white blood cells due to the neutrophil component.

Keywords

dog, inflammation, joint, acute phase protein, rheumatoid factor, C-reactive protein, alkaline phosphatase.