UDC: 619: 617.713-089.843
DOI: 10.36871/vet.zoo.bio.202209003
Authors
Sergey V. Saroyan,
Sergey V. Komarov,
Moscow State Academy of Veterinary Medicine
and Biotechnology – MVA by K. I. Skryabin,
Moscow, Russian Federation
Abstract
This article summarizes clinical results in treatment of deep corneal ulcers and descemetocele,
in which keratoplasty with autologous cornea was used. Deep corneal ulcers are followed by an
acute inflammatory process and high risk of developing complications leading to vision loss. Conservative
treatment of such pathologies is long and not always successful. Keratoplasty for corneal
transplantation is considered an effective method. The outcome of an operation depends on the transplanted
material and the tactics of postoperative treatment. The present study involved 12 animals
and evaluated the effectiveness of using autologous cornea for keratoplasty, which was followed by
post-operative treatment using a regenerative drug. The authors describe the clinical picture, the
techniques involved in the operation, and the results following the dynamic observation of animals.
The results show that the use of autologous cornea for deep corneal ulcers can be an effective
treatment method. There was no rejection in any of the 12 examined cases, the morphofunctional
characteristics of the cornea were preserved. The post-operative treatment included a regenerative
drug. The use of a regenerative drug accelerated the healing process, allowed to preserve the transparency
of the cornea and reduce the risks of transplant rejection.
Keywords
corneal ulcer, corneal sequestrum, autologous corneas, keratoplasty, corneal grafting, regenerative medicine.
