UDC 619: 615.038
DOI: 10.36871/vet.zoo.bio.202307002
Authors
Sergey V. Engashev,
Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Mikhail D. Novak,
Olga V. Evdokimova,
Alexandra I. Novak,
Ryazan State Medical University, Ryazan, Russia
Ekaterina S. Engasheva,
Federal State Budget Scientific Institution «Federal Scientific
Centre VIEV», Moscow, Russia
Abstract
The purpose of the research was to study the effectiveness of the drug ANANDIN 10 % (LLC «AVZ
S-P») in respiratory and gastrointestinal diseases of young cattle in comparison with the complex
antibacterial drug Sulteprim. To implement the main tasks after the use of the immunomodulator,
clinical and laboratory (hematological, biochemical) studies of animals were carried out.
Experiments on the study of the immunomodulator were carried out on 52 Holstein calves 1–1,5
months of age in a large dairy complex in the Central region of the Russian Federation. Based on
the results of the clinical examination, five experimental and two control groups of eight calves each
were formed. Symptoms of respiratory and gastrointestinal diseases were detected in most of the
animals selected for the experiment.
Based on the results of the studies, it was found that ANANDIN 10 % injection solution (LLC «AVZ
S-P») has a pronounced immunomodulatory and immunostimulating activity in doses designed for
cattle. The drug is recommended for prophylactic use in cattle at a dose of 0,02 ml/kg twice with an
interval of 48 hours before primary, re-vaccination or in the same way before revaccination against
infectious diseases. In the complex therapy of severe forms of respiratory diseases in calves, the immunomodulator
should be administered at a dose of 0,08 ml/kg three times at intervals of 3 and 10 days.
Keywords
cattle, calves, respiratory and gastrointestinal diseases, immunomodulator, Anandin 10 %, hematological and biochemical studies
