UDC 619: 616.127
DOI: 10.36871/vet.zoo.bio.202402006
Authors
Yulia S. Kruglova,
Zhora Yu. Muradyan,
Svetlana F. Nazimkina,
Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Abstract
Dogs of the Labrador breed are most predisposed to the formation of a heart tumor (30 %), while
no clear correlation was found in other breeds. The experimental group represents a rather
small and diverse breed base, which makes reliable identification of breed predisposition difficult.
In most cases, cells without sharp signs of atypia were observed in the effusion fluid (80 %),
in 30 % of cases the cells had pronounced atypia, and in 30 % reactive mesothelium was found in
smears. It is important to note that reactive mesothelium is not a reliable marker of a tumor process,
since it can be normal during proliferation, as well as cell atypia, which is often observed with
constant and active mitostatic processes.
The most informative method is histology and echocardiography. In 8 out of 10 cases, histological
examination confirmed a cardiac tumor, while in 8 out of 10 cases the tumor was visualized on
echocardiography. Cytological examination gave reasons to suspect a tumor in 3 out of 10 cases of
mesothelioma or absence of visualization on echocardiography, but at present there are no methods
capable of differentiating mesothelioma cells from reactive mesothelium either cytologically or
histologically.
Keywords
diagnostics, oncology, pericardial effusion, cardiac tumor, histological examination, echocardiography, cytological examination
