DOI: 10.36871 / vet.san.hyg.ecol.201801015
UDC 619: 615.9: 611.36-91

Authors

V. I. EGOROV, CAND. BIOL. SCIENCE HEAD OF THE LABORATORY
K.F. KHALIKOVA, CAND. BET. SCIENCE, SENIOR SCIENTIFIC EMPLOYEE
G.R. YAMALOVA, JUNIOR SCIENTIFIC EMPLOYEE, APPLICANT
D.V. ALEEV, CAND. BIOL. SCIENCE, SENIOR RESEARCH FGBNU "FEDERAL CENTER OF TOXICOLOGICAL, RADIATION AND BIOLOGICAL SAFETY"

Abstract

The article presents the results of clinical, hematological, biochemical and pathomorphological studies of white rats with thiacloprid poisoning with the use of therapeutic agents.
The animals of the control group received thiacloprid intragastrically, the rats of the experimental groups received thiacloprid and medical preparations (magnesium sulfate, novocaine, xymedon, diproxim, sodium bromide, glucose). In the course of the experiments, the clinical condition of the animals, the consumption of feed and water, the survival rate and the pathological anatomical picture were studied. To determine hematological and biochemical studies, blood was collected from rats by decapitation.
According to the results of the studies, it was found that the combination of magnesium sulfate and novocaine is most effective as a therapeutic agent for poisoning animals with thiacloprid. As a result, animal survival was 83,3%. The effectiveness of the treatment is confirmed by hematological, biochemical and pathomorphological studies.

Keywords

pesticides, neonicotinoids, thiacloprid, hematological, biochemical and pathomorphological studies, therapeutic agents, rats.