UDC 636.5.087.69
doi: 10.36871/vet.san.hyg.ecol.202104019
Authors
Lyubov L. Zakharova
Natalia A. Brichko
Georgy А. Zhorov
Viktor N. Obryvin
Svetlana V. Lemiyaseva
All-Russian Research Institute of Veterinary Sanitation, Hygiene and
Ecology – Branch of Federal Scientific Center – K. I. Skryabin, Ya. R. Kovalenko
All-Russian Research Institute of Experimental Veterinary Medicine, Russian
Academy of Sciences, Moscow, Russian Federation
Abstract
The environmental consequences of technogenic pressure pose a real
threat to the health of the population and animals. The main danger to humans is
the presence of pollutants of radiation and chemical nature in food.
The production of animal products that meet the regulatory requirements, and
the ensure of veterinary and sanitary welfare in regions with increased anthropogenic
load is impossible without the use of effective methods of reduce the intake
and accumulation of pollutants in the organism of animals. Therefore, in areas with
a difficult environmental situation, when performing general detoxification, it is
necessary to use a wider range of pharmacological agents, including antioxidants,
immunomodulators, vitamin and mineral supplements and other biologically active
substances that compensate for the negative effects that develop in the body as
a result of exposure to harmful ecological factors, contribute to the restoration of
health, increase the productivity of farm animals and product quality. In this regard,
the combined use of anti-toxic and biologically active substances in the composition
of sorption-detoxifying complexes is rational.
As a result of testing the effectiveness of seven samples of sorption-detoxifying
complex compositions in terms of their effect on the accumulation of Cd and Pb in
the body of white rats, it was found that studied formulations reduce their intake to
organs and tissues by 1,2-2,9 times, depending on the composition of the detoxifier,
both separately and with the presence of heavy metals when combined with
radioactive substances in the feed.
Keywords
cadmium, lead, radionuclides, cumulation, sorption-detoxifying complexes, white rats