UDC 619: 614.48
doi: 10.36871/vet.san.hyg.ecol.202301018

Authors

Gulizar Sh. Shcherbakova,
Galina I. Pavlenko,
Natalia S. Pavlova,
Vasily I. Dorozhkin,
All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation

Abstract

An urgent problem of veterinary science and practice is the search for new highly effective domestic disinfectants that would improve the sanitary quality of products, raw materials and feed of animal origin, as well as animal productivity and ensure the country's well-being in infectious diseases. The most promising in this regard are composite preparations containing several compatible active substances (AS) from various groups of chemical compounds. The new disinfectant «Dezinol Vet» contains glutaraldehyde, glyoxal, a mixture of QAC (alkyldimethylbenzylammonium chloride and idecyldimethylammonium chloride) as an active ingredient. When determining the acute toxicity and cumulative properties of «Dezinol Vet», it was found that at a working concentration (5,5% in water) when injected into the stomach, LD50 was more than 5000 mg/kg, which corresponds to the 4th hazard class (low-toxic compounds) according to GOST 12.1.007-76. No material cumulation of the agent was revealed, a weak functional cumulation was shown. Given that all changes have been canceled only at the level of doses and concentrations that are several times higher than recommended, it is possible to exclude the real danger of this product for animals under the conditions recommended for its use.

Keywords

acute toxicity, cumulative properties, Dezinol Vet, disinfectant, disinfection