UDC 619: 636.23: 615.2
doi: 10.36871/vet.san.hyg.ecol.202401018

Authors

Vladimir G. Tyurin,
All-Russian Research Institute for Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation; Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Scriabin, Moscow 109472, Russian Federation
Vladimir G. Semenov,
Anastasia P. Semenova,
Alexey N. Porfiriev,
Alexey G. Antonov,
Chuvash State Agrarian University, C heboksary 428003, Chuvash Republic, Russian Federation

Abstract

This article data on differentiated counting of the number of leukocytes are given, as well as the dynamics of total protein and protein fractions in the blood of animals, indicating the level of metabolic processes in a living organism, is determined.
It has been established that intramuscular application of experimental biological preparations to cows 65-60, 45-40 and 25-20 days before calving stimulates the process of hematopoiesis, activates cellular factors of non-specific resistance (physiological leukocytosis, moderate eosinophilia and neutropenia with a right shift of the nucleus, lymphocytosis). The most pronounced effect was noted with three injections of the complex biological product Prevention-N-A-M.
Biological preparations Prevention-N-A-M and PS-7 stimulate protein synthesis (albumins, α-, β-, γ-globulins) in the body before and after calving.
The obtained results testify to the effectiveness of the tested biopreparations and make it possible to scientifically substantiate the feasibility of their use in animal husbandry as an effective way to increase the resistance of the body of cows, which can significantly improve their health and reduce the risk of diseases.

Keywords

cows, biological products, Prevention-N-A-M, PS-7, blood serum, blood proteins, leukocyte count