DETERMINING THE SENSITIVITY OF A MICROBIOLOGICAL METHOD FOR DETECTION OF ANTIBACTERIAL DRUGS IN FISH

UDC 619: 614.31: 637.56
doi: 10.36871/vet.san.hyg.ecol.202401006

Authors

Veronica S. Babunova,
Irina S. Osipova,
Elizaveta A. Denisova,
Galina M. Goryainova,
Luiza.V. Arsenyeva,
Petr A. Popov,
All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences, Moscow 123022, Russian Federation

Abstract

The article presents experimental data on expanding the spectrum of detectable groups of antibiotics according to GOST R 55481-2013. The sensitivity for the fluoroquinolone group was 100 μg/kg. For the cephalosporin group, sensitivity ranged from 50 to 100 μg/kg, and for the aminoglycoside group, from 50 to 500 μg/kg. The sensitivity of lincosamides, nitrofurans and macrolides is 100 μg /kg. The method is insensitive to the amphenicol group (5000 μg/kg). The advantages of this method are that it is quite inexpensive, accessible and the duration of the analysis is only 6...7 hours.

Keywords

antibacterial substances, antibiotics, bioluminescent method, immunomicrochip technology, fish, fish products, aquaculture, screenin