INFLUENCE OF IMMUNOMODULATION BY PROBIOTICS ON THE IMMUNO-PHYSIOLOGICAL STATUS OF AQUACULTURE OBJECTS

DOI: 10.26155 / VET.ZOO.BIO.201904005
UDC 639.3

Authors

G. I. PRONINA
ALL-RUSSIAN RESEARCH INSTITUTE OF IRRIGATION FISH PRODUCTION (FGBNU VNIIR)

Abstract

One of the ways to increase the immunity of aquaculture objects is to use immunomodulators as a feed additive. This work presents a study of the effect of the probiotic Bacillus subtilis on carp immunity. It was revealed that in fish treated with a probiotic, immunity to saprolegniosis is enhanced, weight gain, the amount of hemoglobin (by 15%) and almost 2 times the red blood cells increase significantly. In the leukogram of these fish, an increase in metamyelocytes is noted. In the experimental group of fish, the average cytochemical coefficient of the lysosomal cationic protein content in neutrophils does not change and the proportion of these cells in the leukogram is preserved, in contrast to the control, where these indicators significantly increase. Probably, the activation of leukopoiesis in the experimental group occurred due to the expenditure of neutrophils and cationic protein in the lysosomes of these cells in the process of immune defense.

Keywords

carp Cyprinus carpio L., immunomodulators, probiotic Bacillus subtilis, Saprolegnia parasitica, immunity, leukocyte formula, cytochemical coefficient.