UDC 636.13: 575
DOI: 10.26155/vet.zoo.bio.202003008
Authors
S. A. Zinov’eva
Candidate of Biological Sciences, Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K. I. Skryabin,
L. A. Khrabrova
Doctor of Agricultural Sciences, Professor, All-Russian Research Institute of Horse Breeding,
S. I. Sorokin
Candidate of Agricultural Sciences, Head of the HorseGen Laboratory,
N.V. Blokhina
Candidate of Agricultural Sciences, All-Russian Research Institute of Horse Breeding,
A. A. Zelenchenkova
Junior Researcher, Federal State Budgetary Scientific Institution “Federal Scientific Center of Animal Husbandry - VIZH named after Academician L.K. Ernst "
Abstract
Myostatin, encoded by the MSTN gene, is a regulator of skeletal muscle growth in many mammalian species, including the horse. The objective of our research was to study the polymorphism of the myostatin gene MSTN g.66493737 T> C in sports horses and nine local breeds, as well as assess the hopping qualities of horses with different types of myostatin. The results of a study of myostatin polymorphism by the g.66493737 T> C nucleotide substitution in horses indicate that the MSTNC mutant allele is typical of many local breeds and is found in Altai, Vyatka, Polesskaya, Tavda and Tuva horses with a fairly high frequency (0,100-0,286). In sporting horses of domestic breeding, the frequency of occurrence of the MSTNC allele was noticeably lower than in representatives of foreign breeding - 0,063 and 0,143, respectively. A comparative assessment of the success of the horses of the two groups in the obstacle-climbing competitions showed the advantage of carriers of the heterozygous genotype MSTN C / T both in the number of starts and in the average number of prizes won (P = 0,95).
Keywords
native breeds, genetic testing, horses, myostatin, mutation.
