DOI: 10.36871/vet.zoo.bio.202012002
UDC 617.1

Authors

N. A. Slesarenko
Doctor of Biological Sciences, Professor, Head of the Department of Anatomy and Histology of Animals after Professor A. F. Klimov, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
A. G. Shilkin
Candidate of Medical Sciences, Director of Veterinary Ophthalmology Center, Moscow, Russian Federation
U. E. Lukashina
Graduate student of the Department of Anatomy and Histology of Animals after Professor A. F. Klimov, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation

Abstract

The article reflects the influence of corneal collagen crosslinking on changes in the morphofunctional signs of the corneal stroma. Data on changes in the anterior layers of the stroma, which are expressed by a compact packing of fibers without signs of even minimal edema, as well as a demarcation line separating the area of impact from the indifferent zone, are scientifically substantiated. Clinical observation of cats and dogs after keratoplasty using a crosslinking modified cornea showed the most favorable course of the postoperative period which was expressed in an increase in the resistance of the collagen matrix of the donor tissue to collagenases which is especially important when using large and giant transplants.

Keywords

crosslinking, stratification, demarcation line, keratopathy, keratoplasty.