Etiopathogenetic specificity and prospects of phage therapy in infectious keratoconjunctivitis in cattle

DOI: 10.36871/vet.zoo.bio.202103004
UDC 617.711-002: 636.2

Authors

N. V. Pimenov
Professor of the Russian Academy of Sciences, Doctor of Biological Sciences, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin», Moscow, Russian Federation
M. Aref Agah
Teaching Assistant, Faculty of Agriculture, Badgis University, Qala i Naw city, Badghis, Afghanistan Research Student, Faculty of Veterinary Medicine, Department of Biology and Pathology of Small Domestic, Laboratory and Exotic Animals, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K.I. Skryabin», Moscow, Russian Federation
G. Sh. Navruzshoeva
Candidate of Veterinary Sciences, Associate Professor, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K.I. Skryabin», Moscow, Russian Federation

Abstract

Infectious bovine keratoconjunctivitis (IBK) is a bacterial eye disease affecting cattle worldwide. The main etiological role in IBK belongs to Moraxella spp. (including in associations with Staphylococcus spp., Streptococcus spp., Pseudomonas aeruginosa, E. coli, Proteus). Persistence factors and antimicrobial resistance of these bacteria, reduce the effectiveness of traditional treatment measures for IBK.
New strategies for combating bacterial infections set up prospects for the use of bacteriophages. The paper presents data substantiating the relevance of the development of a therapeutic and prophylactic method of phage processing and an agent based on lytically properties of bacteriophages to combat infectious keratoconjunctivitis in cattle.

Keywords

Infectious bovine keratoconjunctivitis, cattle, bacteriophage, phage therapy, antimicrobial resistance.