DOI: 10.36871/vet.zoo.bio.202104003
UDC 636.2

Authors

Yu. N. Kramer
Researcher at the Laboratory of Quality and Standardization of Bacterial Medicines, All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russian Federation
N. V. Pimenov
Professor of the Russian Academy of Sciences, Doctor of Biological Sciences, Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation

Abstract

The study of the antigenic activity of vaccines used against anaerobic enterotoxemia of calves was carried out. The level of antibodies during immunization with the vaccines: «Polyvalent toxoid Clostridium perfringens against anaerobic enterotoxemia of calves» and the associated vaccine against clostridiosis «Klostbovak-8» – was comparable. Credits to all types of the pathogen was protective in the application of the toxoid. At 40–50 days of age, the level of antibodies was significantly higher when using polyvalent toxoid. No antibodies were detected in the control group.

Keywords

antigenic activity, anaerobic enterotoxemia, calves, toxoid, vaccines.