DOI: 10.36871/vet.zoo.bio.202108005
UDC 579.62: 615.371: 636
Authors
O. E. Zinovieva
Researcher, Central Scientific and
Methodological Veterinary Laboratory,
Moscow, Russian Federation
S. V. Zyuzgina
Senior Researcher, Central Scientific and
Methodological Veterinary Laboratory,
Moscow, Russian Federation
O. V. Babicheva
Senior Researcher, All-Russian State Center for Quality and
Standardization of Medicines for Animals and Feed
Moscow, Russian Federation
A. R. Balayeva
Head of the Department of Serology and Leptospirosis, Central
Scientific and Methodological Veterinary Laboratory,
Moscow, Russian Federation
S. N. Marzanova
Candidate of Biological Sciences, Associate Professor,
Moscow State Academy of Veterinary Medicine
and Biotechnology – MVA by K. I. Skryabin,
Moscow, Russian Federation
Abstract
Leptospirosis is one of the most frequently registered diseases among animals not only on the
territory of the Russian Federation, but also abroad. The disease is included in the list of quarantine
diseases, every year veterinary laboratories conduct serological studies using the microagglutination
reaction (МАТ) within the framework of government work, epizootic monitoring and
paid types of research. So for 2020, 1 268 749 probes from different animal species were conducted,
and 25 401 were received, which is 2% of the total number of received probes. The largest number of
seropositive animals is registered among cattle 1,30% of the total number of probes studied, among
pigs and horses the number of positive results is 0,29% and 0,28% is for small cattle. Reacting animals
are registered less, only 0,11%, other animal species reach 0,02% of the total volume of probes
studied in the Russian Federation.
The analysis of spreading of the serogroups among different animal species was carried out and
the etiological structure of leptospirosis was derived. For most animals are typical a mixed etiology
of the disease, which takes 35,38% of all positive probes, a large volume of which falls on probes
with registration for only one of the serogroups, namely: Icterohaemorrhagiae – 17,55%, Tarassovi
– 11,40%, Pomona – 8,94% and Sejroe – 8,01% of the total volume of positive probes.
The article presents a list of the consumer market of drugs (imported and domestic production)
mono- and associated vaccines against leptospirosis of farm animals. It specifies the manufacturing
companies, the trade name of the drug and the quantitative composition of leptospirosis serogroups
in vaccines registered in the territory of the Russian Federation.
Keywords
leptospirosis, vaccine, immunity, serogroup accessory, microagglutination test (МАТ).
