UDC 619: 616.72-002: 636.3
DOI: 10.36871/vet.zoo.bio.202308001
Authors
Mikhail D. Kachalin,
Sergey V. Posyabin,
Elena N. Borkhunova,
Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Abstract
The article presents data on the results obtained when creating a model of induced gonarthrosis in sheep. Creating a model of osteoarthritis, which is easily executable, gives a stable result and corresponds to osteoarthritis in clinical and morphological terms – an important task of arthrology. We adapted the method of modeling osteoarthritis. The method previously used in dogs and laboratory animals is implemented in sheep.The technique consists in desmotomy of the anterior cruciate ligament, which makes it possible to obtain instability in the knee joint, leading to destructive changes in the articular cartilage. The results obtained during the experimental modeling were evaluated on the basis of clinical, visual-diagnostic and morphological methods of the study. The proposed technique is simple to implement, allows to obtain a stable and well-reproduced result. According to clinical signs, the results of computed tomographic studies, macro- and microscopic picture, the process that occurs after the intervention corresponds to osteoarthrosis.
Keywords
gonarthrosis, experimental modeling, sheep, computed tomography, morphology
