UDC 6196616.3: 636.91
DOI: 10.36871/vet.zoo.bio.202401003
Authors
Dmitriy I. Gildikov,
Sergey V. Posyabin,
Valery N. Baymatov,
Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Abstract
The aim of the study was to establish the protective effect of various drugs on rats with experimental
damage to the gastroduodenal zone. The object of the study was Wistar rats (n=84) exposed
to high-power light effect on days 1, 7 and 14. A comprehensive methodological approach was
used, including the study of behavioral reactions, macroscopic assessment of the gastric mucosa
and duodenum 12, light microscopy of histological sections of the adrenal glands.
It was found that intragastric administration of amino acid-based dietary supplements to rats,
at a dose of 0.05 ml per animal, for 14 days, contributes to increased locomotor activity and research
function, which can be regarded as a stress-protective effect aimed at suppressing anxiety-depressive
changes in the behavior of the studied individuals. The protective properties of the studied
dietary supplements, confirmed by an experimental model of damage to the gastroduodenal zone,
are distributed according to the corrective effect as follows: BAD-2, BAD-1, BAD-3.
Keywords
rats, stress, damage to the gastroduodenal zone, amino acids, L-thianine, tryptophan, enteroprotection
